Sunscreen
What sunscreen is safe for pregnancy? What we can and can't say
We could not verify a pregnancy-specific recommendation, so here is what the regulatory record and small studies actually support.
By Artifact Editors, Editorial team
Published · 3 min read

In this article
We can't give you a verified yes or no
Here is the honest answer: we could not confirm a pregnancy-specific sunscreen recommendation from the American Academy of Dermatology, the American College of Obstetricians and Gynecologists, or the NIH. Our attempts to load those professional-society pages failed, so their guidance remains unverified on our end.
What we could verify is the regulatory and research picture, which is narrower than most headlines suggest. Treat any product that calls itself safe in pregnancy as claiming more than the evidence supports.
Mineral filters are the better-characterized option
Bottom line: if you want the ingredients with the cleanest record so far, look for zinc oxide and titanium dioxide. FDA's 2019 proposed rule judged both generally recognized as safe and effective, while data gaps remained for 12 other active ingredients. FDA was explicit that those gaps did not mean the other 12 are unsafe (FDA proposed rule fact sheet; FDA media briefing).
Two caveats. The rule was a proposal, and the comment period closed in June 2019 with about 15,000 comments. We found a 2021 order but not a confirmed final rule, so check the FDA proposed administrative order for current status. We also did not retrieve absorption data for zinc oxide or titanium dioxide, so better characterized describes the regulatory record, not proof of safety in pregnancy.
Oxybenzone is the ingredient with the most pregnancy signal
Bottom line: if you are avoiding one ingredient, the research points most often at oxybenzone, but the signal is observational and inconsistent.
Absorption is the reason it matters. An earlier study in 24 volunteers showed sunscreen actives were absorbed, and a larger follow-up confirmed it, including for 6 of the 12 flagged ingredients (Matta et al., JAMA). Every tested ingredient stayed above FDA's 0.5 ng/mL threshold for at least 23 hours. For oxybenzone and homosalate, more than half of participants stayed above it for up to 21 days.
Absorption is not the same as harm. The authors concluded that clinical significance still needs study (JAMA maximal-use trial). Oxybenzone is also described as the most bioavailable UV filter after topical use, appearing in plasma and urine (Gonzalez et al., 2008).
The pregnancy studies are small and point in different directions
Bottom line: none of these studies shows that sunscreen harms a pregnancy, and none shows it protects one. They are observational and mostly small, and they measure exposure through urine, which is an imperfect snapshot.
| Outcome | Study | What it found | How much weight |
|---|---|---|---|
| Late-pregnancy glucose | 217 women from a fertility-clinic cohort ([perinatal urinary study](https://pmc.ncbi.nlm.nih.gov/articles/PMC7189447/)) | Higher first-trimester levels linked to lower glucose (103.4 vs 114.6 mg/dL, top vs bottom quartile); second-trimester results mixed | Low: small, subfertile sample, counterintuitive direction |
| Thyroid | 106 pregnant women in Puerto Rico; 183 in Denmark ([thyroid study](https://pmc.ncbi.nlm.nih.gov/articles/PMC6470297/)) | Lower free T3 in one group; no association with maternal T3 or T4 in the other | Low: conflicting results |
| Birth size | EARTH cohort ([birth size study](https://pmc.ncbi.nlm.nih.gov/articles/PMC5899953/)) | Higher birth size (beta = 153 g, 95% CI 74–234) | Low: association only, causation not established |
| Malformation | One study ([review of safety questions](https://pmc.ncbi.nlm.nih.gov/articles/PMC8953895/)) | Association with Hirschsprung's disease, but urine was collected after birth | Very low: does not reflect prenatal exposure |
| Assisted reproduction | 304 women undergoing ART ([ART study](https://pmc.ncbi.nlm.nih.gov/articles/PMC6550292/)) | Positive associations with implantation, clinical pregnancy, and live birth | Low: points away from harm, not proof of benefit |
Exposure is already common. One pregnancy pilot found mean urinary benzophenone-3 of about 88 μg/L, roughly twice the NHANES average for women aged 30 to 44 (pilot study). That makes the research question about background exposure, not a rare event.
What we'd do with this, and where to check
Bottom line: the evidence supports a measured approach, not panic. We found nothing in the research that tells you to stop wearing sunscreen during pregnancy.
- Look for zinc oxide or titanium dioxide on the label as the better-characterized filters.
- Check the active ingredient list for oxybenzone and homosalate, and choose a product without them if you can.
- Pair sunscreen with shade and clothing rather than relying on one product.
- Ask your OB or midwife, and check the AAD and ACOG pages directly, since we could not verify them.
For more on sunscreen ingredients and labels, see our sunscreen guide.
Frequently asked questions
Is zinc oxide safe during pregnancy?
The record is better than for most filters. FDA's 2019 proposed rule judged zinc oxide generally recognized as safe and effective. We did not find pregnancy-specific absorption data for it, so better characterized is the most we can say.
Should I avoid oxybenzone while pregnant?
The research flags oxybenzone most often, but the pregnancy studies are small, observational, and conflicting. We found no trial showing harm and no trial showing benefit from avoiding it. Choosing a product without it is a low-cost precaution to discuss with your clinician.
Do the AAD and ACOG recommend a specific sunscreen?
We couldn't verify it, because their pages did not load for us. Check their websites directly, and ask your OB or midwife for a recommendation that fits your health history.
Sources (13)
- FDA Fact Sheet: FDA Proposed Rule – Sunscreen Drug Products for OTC Human Use 2019
- FDA Media Briefing on the Sunscreen Proposed Rule, Feb 21 2019
- FDA Proposed Administrative Order OTC000008 2021
- FDA response document on sunscreen active ingredients
- Matta et al., "Effect of Sunscreen Application on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial," JAMA
- "Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial," JAMA
- Gonzalez et al., "Solid-Phase Extraction and Reverse-Phase HPLC: … Urinary Excretion Pattern of Benzophenone-3," 2008
- "Perinatal urinary benzophenone-3 concentrations and glucose levels among women from a fertility clinic"
- "Associations of maternal exposure to triclosan, parabens, and other phenols with prenatal maternal and neonatal thyroid hormone levels"
- "Preconception and Prenatal Urinary Concentrations of Phenols and Birth Size … EARTH Study"
- "Benzophenone-3, a chemical UV-filter in cosmetics: is it really safe for children and pregnant women?"
- "Urinary concentrations of benzophenone-3 and reproductive outcomes among women undergoing infertility treatment with ART"
- "Urinary Concentrations of Environmental Phenols in Pregnant Women in a Pilot Study of the National Children's Study"



