Skip to content
artifact

Topic

Niacinamide

Niacinamide is a form of vitamin B3 and one of the few skincare ingredients that is both wildly popular and reasonably well studied. People use it for oil, uneven tone, redness, and a shaky skin barrier, and most tolerate it well. Here is what it actually does, where the hype outruns the evidence, how it plays with other actives, and why a 10% serum isn't automatically better than a 5% one.

2 articles

Start here

Niacinamide FAQ

Are niacinamide and niacin the same thing?

No. Both are forms of vitamin B3, but they behave differently on skin. Niacin can cause a flushing sensation, while niacinamide generally doesn't. Niacinamide and nicotinamide are the same compound with two names, so a label using either one is listing the same ingredient.

Can niacinamide cause breakouts or purging?

Usually not from the niacinamide itself. It isn't an exfoliant, so true purging is an unlikely explanation. Breakouts more often trace back to something else in the formula, a heavy texture, or irritation from using too much too soon. Stop the product if you see a pattern, and patch test new ones.

Can you use niacinamide with retinol and vitamin C?

Yes, for most people. Niacinamide is commonly paired with both in routines, and some people find it makes a retinol routine easier to tolerate. If your skin stings, the culprit is usually the total number of actives, not a clash. Add one product at a time and give each a couple of weeks.

What percentage of niacinamide is best?

Much of the research on topical niacinamide uses roughly 2% to 5%, which is a sensible place to start. Products at 10% are common, but there's no solid evidence that more is better, and higher percentages are more likely to sting or irritate. The overall formula and your tolerance matter as much as the number.

Is niacinamide safe during pregnancy?

Probably low risk, but we can't give you a clean yes. Topical niacinamide is common in everyday skincare, yet pregnancy-specific data is limited. Ask your OB or dermatologist before using it, especially at higher strengths, and don't start oral supplements without medical guidance.

The Artifact Edit

One smart email a week. What’s worth buying, what’s hype, and why.